Magnetic cell enrichment
Do you need to study circulating tumor cells (CTCs)? These cells can also be isolated with a combination of magnetic cell enrichment and flow cytometry. We can take a blood sample and enrich for the non-leukocyte cell population. After isolating these cells, you can put them into a functional assay.
- Positive selection uses an antibody specific to your cell of interest to pull it out of a mixed population of cells.
- Negative selection is used to remove cells you are not interested in to decrease the risk of activating your cells with bound antibodies, leaving your cells “untouched”.